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Supplements · Magnesium

Best Magnesium Supplements 2025

Magnesium is involved in over 300 biochemical reactions in the body — yet studies estimate 50–60% of Americans don't get enough. Poor sleep, muscle cramps, anxiety, and constipation are all common signs of deficiency. The problem is there are a dozen different forms of magnesium, and they're not all equally effective.

Key point: Magnesium oxide (the cheapest form, found in most drugstore vitamins) has poor absorption. Glycinate and malate absorb significantly better.

Best Magnesium Supplements Ranked

#1 — Best Overall (Sleep & Stress)

Thorne Magnesium Bisglycinate

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200mg per serving
Glycinate form
NSF Certified

Magnesium glycinate is the best form for sleep and anxiety because glycine itself is calming. Thorne's version uses bisglycinate (two glycine molecules), which has even better absorption. This is the recommended form for people on GLP-1 medications — gentle on the stomach, highly bioavailable, and no laxative effect. Take 200–400mg before bed.

#2 — Best Powder (Constipation)

Natural Vitality Calm Magnesium Citrate

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Citrate form
Powder drink
Best seller

The best-selling magnesium supplement on Amazon for years. Magnesium citrate absorbs well and has a mild laxative effect — which is actually useful for GLP-1 users who experience constipation (a common side effect). Mixed into warm water before bed as a calming ritual, this has a dedicated following. Raspberry Lemon flavor is the most popular.

#3 — Best for Energy

Doctor's Best Magnesium Glycinate/Malate

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200mg elemental Mg
Chelated
Great value

TRAACS chelated magnesium — one of the most bioavailable forms available. The malate component supports energy production (malic acid is involved in the Krebs cycle), making this a good daytime option. High elemental magnesium per serving, no fillers, well-priced. One of the most recommended by integrative medicine physicians.

#4 — Best Budget

NOW Magnesium Citrate

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120 capsules
~$0.10/serving
GMP certified

NOW is one of the most respected budget supplement brands. Their magnesium citrate capsules deliver 200mg of elemental magnesium at about 10 cents per serving. GMP certified, widely available, consistently well-reviewed. If you want a no-frills citrate supplement without paying a premium, this is the reliable choice.

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